• Rev Assoc Med Bras (1992) · Jan 2020

    Review

    Acute kidney injury in cancer patients.

    • Bruno Nogueira César and Marcelino de Souza Durão Júnior.
    • Disciplina de Nefrologia, Universidade Federal de São Paulo, São Paulo, SP, Brasil.
    • Rev Assoc Med Bras (1992). 2020 Jan 13; 66Suppl 1 (Suppl 1): s25-s30.

    AbstractThe increasing prevalence of neoplasias is associated with new clinical challenges, one of which is acute kidney injury (AKI). In addition to possibly constituting a clinical emergency, kidney failure significantly interferes with the choice and continuation of antineoplastic therapy, with prognostic implications in cancer patients. Some types of neoplasia are more susceptible to AKI, such as multiple myeloma and renal carcinoma. In cancer patients, AKI can be divided into pre-renal, renal (intrinsic), and post-renal. Conventional platinum-based chemotherapy and new targeted therapy agents against cancer are examples of drugs that cause an intrinsic renal lesion in this group of patients. This topic is of great importance to the daily practice of nephrologists and even constitutes a subspecialty in the field, the onco-nephrology.

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