• Critical care clinics · Jul 2020

    Review

    Overview of Management of Intermediate- and High-Risk Pulmonary Embolism.

    • Victor F Tapson and Aaron S Weinberg.
    • Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Thalians Building Room w155, 8730 Alden Drive, Los Angeles, CA 90048, USA. Electronic address: victor.tapson@cshs.org.
    • Crit Care Clin. 2020 Jul 1; 36 (3): 449-463.

    AbstractAnticoagulation is the cornerstone of acute pulmonary embolism (PE) therapy. Intermediate-risk (submassive) or high-risk (massive) PE patients have higher mortality than low-risk patients. It is generally accepted that high-risk PE patients should be considered for more aggressive therapy. Intermediate-risk patients can be subdivided, although more than simply categorizing the patient is required to guide therapy. Therapeutic approaches depend on a prompt, detailed evaluation, and PE response teams may help with rapid assessment and initiation of therapy. More clinical trial data are needed to guide clinicians in the management of acute intermediate- and high-risk PE patients.Copyright © 2020 Elsevier Inc. All rights reserved.

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