• Ann. Intern. Med. · Dec 2019

    Case Reports

    Cases in Precision Medicine: A Personalized Approach to Stroke and Cardiovascular Risk Assessment in Women.

    • Natalie A Bello, Eliza C Miller, Kirsten Lawrence Cleary, and Ronald Wapner.
    • Columbia University Irving Medical Center, New York, New York (N.A.B., E.C.M., K.L.C., R.W.).
    • Ann. Intern. Med. 2019 Dec 3; 171 (11): 837842837-842.

    AbstractCardiovascular disease is the leading cause of death among women in the United States, and stroke is third. This article uses a case scenario to examine female sex-specific cardiovascular risk factors across the lifespan and describes a precision medicine-based approach to risk factor modification and primary prevention. It also presents recent updates to the role of genetic testing and polygenic risk scores for the prediction of stroke and cardiovascular disease.

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