• Infect. Dis. Clin. North Am. · Dec 2016

    Review

    Ventilator-Associated Events and Their Prevention.

    • Noelle M Cocoros and Michael Klompas.
    • Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, 401 Park Street, Suite 401, Boston, MA 02215, USA.
    • Infect. Dis. Clin. North Am. 2016 Dec 1; 30 (4): 887-908.

    AbstractThe Centers for Disease Control and Prevention shifted the focus of safety surveillance in mechanically ventilated patients from ventilator-associated pneumonia to ventilator-associated events (VAEs) in 2013. The shift was designed to increase the objectivity and reproducibility of surveillance and to encourage quality-improvement programs to tackle a broader array of complications in mechanically ventilated patients. Prospective intervention studies have found that minimizing sedation, increasing the use of spontaneous awakening and breathing trials, and conservative fluid management can lower VAE rates and decrease duration of mechanical ventilation. Additional strategies to prevent VAEs include early mobility programs, low tidal volume ventilation, and restrictive transfusion thresholds.Copyright © 2016 Elsevier Inc. All rights reserved.

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