• Med Princ Pract · Jan 2019

    Case Reports

    Rapid Changes of Thyroid Function in a Young Woman with Autoimmune Thyroid Disease.

    • Christian Trummer, Verena Schwetz, Felix Aberer, Marlene Pandis, Elisabeth Lerchbaum, and Stefan Pilz.
    • Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria, christian.trummer@medunigraz.at.
    • Med Princ Pract. 2019 Jan 1; 28 (4): 397-400.

    ObjectiveA conversion from Hashimoto's thyroiditis to Graves' disease and vice versa leads to diagnostic and therapeutic challenges.Clinical Presentation And InterventionA 30-year-old female presented with overt hyperthyroidism and negative thyroid-stimulating hormone receptor antibodies (TRAbs). Since hashitoxicosis was assumed, the patient was treated with propranolol. Within the next few weeks, the patient developed severe overt hypothyroidism, which was treated with levothyroxine. However, after several more weeks, she presented with overt hyperthyroidism once again, this time showing elevated TRAbs.ConclusionWe suggest educating patients and physicians to recognize changes in thyroid function and close monitoring of unclear cases of overt hyperthyroidism.© 2019 The Author(s) Published by S. Karger AG, Basel.

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