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Ugeskrift for laeger · Feb 2015
Review[Ischaemic preconditioning for protection against reperfusion injury in non-cardiac surgery].
- Sarah Ekeløf and Ismail Gögenur.
- Kirurgisk Afdeling, Køge Sygehus, Lykkebækvej 1, 4600 Køge. sarahekeloef@gmail.com.
- Ugeskr. Laeg. 2015 Feb 9; 177 (7).
AbstractRemote ischaemic preconditioning is a non-invasive intervention that is done by transient occlusion of the blood flow to a limb with a blood pressure cuff. The intervention initiates a systemic endogenous protective response, which may confer multi-organ protection against acute ischaemia reperfusion injury. Originally discovered as a therapeutic strategy in cardiac surgery for protecting the myocardium against ischaemia reperfusion injury, it has been discovered that remote ischaemic preconditioning may confer protection against surgical stress and reperfusion injury in non-cardiac surgery.
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