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- David Birnie, Andrew C T Ha, Lorne J Gula, Santabhanu Chakrabarti, Rob S B Beanlands, and Pablo Nery.
- Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4 W7, Canada. Electronic address: dbirnie@ottawaheart.ca.
- Clin. Chest Med. 2015 Dec 1; 36 (4): 657-68.
AbstractStudies suggest clinically manifest cardiac involvement occurs in 5% of patients with pulmonary/systemic sarcoidosis. The principal manifestations of cardiac sarcoidosis (CS) are conduction abnormalities, ventricular arrhythmias, and heart failure. Data indicate that an 20% to 25% of patients with pulmonary/systemic sarcoidosis have asymptomatic (clinically silent) cardiac involvement. An international guideline for the diagnosis and management of CS recommends that patients be screened for cardiac involvement. Most studies suggest a benign prognosis for patients with clinically silent CS. Immunosuppression therapy is advocated for clinically manifest CS. Device therapy, with implantable cardioverter defibrillators, is recommended for some patients. Copyright © 2015 Elsevier Inc. All rights reserved.
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