• Francesco Raimondi, Javier Rodriguez Fanjul, Salvatore Aversa, Gaetano Chirico, Nadya Yousef, Daniele De Luca, Iuri Corsini, Carlo Dani, Lidia Grappone, Luigi Orfeo, Fiorella Migliaro, Gianfranco Vallone, Letizia Capasso, and Lung Ultrasound in the Crashing Infant (LUCI) Protocol Study Group.
• Division of Neonatology, Department of Translational Medical Sciences, Università "Federico II" di Napoli, Naples, Italy. Electronic address: raimondi@unina.it.
• J. Pediatr. 2016 Aug 1; 175: 74-78.e1.

ObjectivesTo evaluate the accuracy of lung ultrasound for the diagnosis of pneumothorax in the sudden decompensating patient.Study DesignIn an international, prospective study, sudden decompensation was defined as a prolonged significant desaturation (oxygen saturation <65% for more than 40 seconds) and bradycardia or sudden increase of oxygen requirement by at least 50% in less than 10 minutes with a final fraction of inspired oxygen ≥0.7 to keep stable saturations. All eligible patients had an ultrasound scan before undergoing a chest radiograph, which was the reference standard.ResultsForty-two infants (birth weight = 1531 ± 812 g; gestational age = 31 ± 3.5 weeks) were enrolled in 6 centers; pneumothorax was detected in 26 (62%). Lung ultrasound accuracy in diagnosing pneumothorax was as follows: sensitivity 100%, specificity 100%, positive predictive value 100%, and negative predictive value 100%. Clinical evaluation of pneumothorax showed sensitivity 84%, specificity 56%, positive predictive value 76%, and negative predictive value 69%. After sudden decompensation, a lung ultrasound scan was performed in an average time of 5.3 ± 5.6 minutes vs 19 ± 11.7 minutes required for a chest radiography. Emergency drainage was performed after an ultrasound scan but before radiography in 9 cases.ConclusionsLung ultrasound shows high accuracy in detecting pneumothorax in the critical infant, outperforming clinical evaluation and reducing time to imaging diagnosis and drainage.Copyright © 2016 Elsevier Inc. All rights reserved.

18 keywords...

hide…