• Spine · Jan 2021

    Risk Factors Associated with Development of Urinary Retention Following Posterior Lumbar Spinal Fusion: Special Attention to the Use of Glycopyrrolate in Anesthesia Reversal.

    • Jeremy D Mormol, Bryce A Basques, Garrett K Harada, Philip K Louie, Kevin Alter, Edward Goldberg, Matthew W Colman, and Howard S An.
    • Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL.
    • Spine. 2021 Jan 15; 46 (2): E133-E138.

    Study DesignThe study is designed as a retrospective cohort study.ObjectiveThe aim of this study was to identify modifiable and nonmodifiable risk factors of postoperative urinary retention in spine surgery patients.Summary Of Background DataPostoperative urinary retention is a common complication in patients undergoing operative procedures requiring anesthesia. Current studies have shown significant risk factors for postoperative urinary retention, but most are nonmodifiable and subsequently of limited usefulness in preventing this complication. Several new studies have shown possible modifiable risk factors, but current data are inconsistent in terms of their statistical significance.MethodsA total of 814 consecutive patients who underwent open posterior lumbar laminectomy and fusion were included in the retrospective cohort study. Pre, intra-, and postoperative characteristics were collected in all patients to identify risk factors for postoperative urinary retention.ResultsGlycopyrrolate use (odds ratio [OR] 2.60; P = 0.001), decreased body mass index (OR 0.96; P = 0.018), previous diagnosis of benign prostate hyperplasia (OR 3.34; P ≤ 0.001), and postoperative urinary tract infection (OR 5.60, P = 0.005) were associated with postoperative urinary retention. Previous history of lumbar spine surgery (OR 0.55; P = 0.019) was associated with decreased rates of postoperative urinary retention.ConclusionGlycopyrrolate use, benign prostate hyperplasia, and postoperative urinary tract infection were independent risk factors for postoperative urinary retention. The use of glycopyrrolate is a potentially modifiable risk factor for postoperative urinary retention.Level of Evidence: 3.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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