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- Laurie J Morrison.
- Rescu, Li Ka Shing Knowledge Institute, St Michael's Hospital, 30 Bond Street, Toronto, ON M5B 1W8, Canada; Division of Emergency Medicine, Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address: Laurie.Morrison@unityhealth.to.
- Crit Care Clin. 2020 Oct 1; 36 (4): 715-721.
AbstractEvidence provides weak support for the routine use of vasopressors in cardiac arrest where the quality of CPR and post arrest care are unknown and the drug is given late. In these pragmatic settings, epinephrine improves clinical outcomes, but does so at the price of increasing the proportion of patients surviving with poor neurologic function at 30 days. In settings where the quality of CPR and post arrest care are optimized the additive effect of epinephrine on clinical outcomes is not significantly different. Well designed efficacy trials are needed where routine cardiac arrest care is optimized.Copyright © 2020 Elsevier Inc. All rights reserved.
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