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- John R Marler and Larry B Goldstein.
- National Institute of Neurological Disorders and Stroke, Bethesda, MD 20817, USA. marlerj@ninds.nih.gov
- Science. 2003 Sep 19; 301 (5640): 1677.
AbstractClinical trial results are not always rapidly incorporated into routine medical practice. This Policy Forum describes a variety of barriers that have impeded the more widespread use of thrombolytic therapy (tPA, tissue plasminogen activator) for selected patients with acute ischemic stroke. These barriers are not insurmountable but will require a concerted effort to overcome.
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