• Neurology India · Jan 2008

    Case Reports

    Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing: response to antiepileptic dual therapy.

    • Ravi Gupta and Manjeet S Bhatia.
    • Department of Psychiatry, University College of Medical Sciences and GTB Hospital, Shahdara, New Delhi-110 095, India. guptaravi_2003@yahoo.co.in
    • Neurol India. 2008 Jan 1; 56 (1): 71-3.

    AbstractShort-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is included among trigeminal autonomic cephalalgias in the International Classification of Headache Disorders-2. Available literature suggests that it responds to anticonvulsants, particularly lamotrigine. However, management of partial responders is difficult and antiepileptic duo-therapy may be an answer to it. Nonetheless, to our knowledge, anticonvulsant combination has never been tried in partial responders to monotherapy. We are presenting a case of SUNCT that had overlapping symptoms with Short-lasting Unilateral Neuralgiform headache attacks with cranial Autonomic features and responded well only to the combination of lamotrigine with carbamazepine. However, lamotrigine had to be stopped as patient developed leucopenia and it resulted in partial recurrence of symptoms.

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