• Wei Luo, Ya Liu, Qiang Zhang, Huifang Zhong, and Jia Deng.
• Department of Respiratory and Critical Care Medicine, Chongqing Jiangbei Hospital of Traditional Chinese Medicine.
• Medicine (Baltimore). 2020 Sep 25; 99 (39): e22012e22012.

BackgroundTraditional Chinese medicine injections (TCMJ) used in the treatment of severe pneumonia have been widely implemented in clinical practice, but their overall efficacy and safety remain unclear. This paper aims to evaluate the efficacy and safety of TCMJ in the treatment of severe pneumonia.MethodsPubMed, EMbase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, WanFang, and the Chongqing VIP Chinese Science and Technology Periodical Database were all searched for randomized controlled trials focusing on the administration of TCMJ for severe pneumonia. Two researchers independently screened titles, abstracts, full texts, and extracted relevant data. The RevMan 5.3 software (The Cochrane Collaboration, Software Update, Oxford, UK) and Stata 14 software (STATA Corporation, College Station, TX) were used for statistical analysis.ResultsThis study summarizes the related randomized controlled trials to assess the effect and safety of TCMJ in the treatment of severe pneumonia.ConclusionThis article provides theoretical support for the clinical application of TCMJ in the treatment of severe pneumonia.Prospero Registration NumberCRD42020185072.

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