• Siyu Qin, Yuanyi Xiao, Zhenhai Chi, Daocheng Zhu, Pan Cheng, Ting Yu, Haiyan Li, and Lin Jiao.
• College of Acupuncture-Moxibustion and Tuina, Jiangxi University of Traditional Chinese Medicine.
• Medicine (Baltimore). 2020 Sep 25; 99 (39): e22262e22262.

BackgroundAnxiety and depression, complications of cancer, are prevalent but often overlooked mental illnesses. Studies have demonstrated that massage therapy is useful in relieving anxiety and depression of cancer survivors. However, the mechanism is still unclear and no systematic review has provided sufficient evidence for the treatment. Therefore, this protocol is carried out to comprehensively evaluate the reliability of cancer patients with anxiety and depression treated by massage.MethodsWe will systematically search the relevant literature from PubMed, Cochrane Library, EMBASE, Web of Science, Wanfang, Chongqing VIP, CNKI and Chinese Biomedical Literature Database from the establishment of the databases to June 1, 2020. In addition, we will only include randomized controlled trials about massage for cancer survivors with anxiety and depression, regardless of language and publication status. Two experienced researchers will separately screen the literature, collect data, analyze data and synthesize data using RevMan V.5.3 software. The quality of the included trials in the study will be assessed by the Cochrane bias risk assessment tool.ResultsThe protocol for the meta-analysis will systematically evaluate the reliability of massage therapy for cancer patients with anxiety and depression.ConclusionThis conclusion will provide an important basis for evaluating whether massage is reliable in treating cancer survivors who feel anxious and depressed.Inplasy Registration NumberINPLASY202060101.

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