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- Chiranjib Chakraborty, Ashish Ranjan Sharma, Manojit Bhattacharya, Garima Sharma, Sang-Soo Lee, and Govindasamy Agoramoorthy.
- Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, West Bengal, India.
- J. Med. Virol. 2020 Nov 1; 92 (11): 2260-2262.
AbstractCOVID-19 leads to mortality of several patients and the cytokine storm is reportedly critical in the patients. To reduce the cytokine storm, we would like to propose the interleukin (IL) 6 receptor (IL-6R) antagonist therapy for the COVID-19 patients. Two humanized monoclonal antibodies are in clinical trial following IL-6R antagonist therapies namely tocilizumab and sarilumab. However, researchers and physicians should look for more IL-6R antagonists for the therapy of cytokine storm syndrome severe acute respiratory syndrome coronavirus 2 infected persons to enhance the therapeutic options for cytokine storm.© 2020 Wiley Periodicals LLC.
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