• Aimin Cui, Jing Zhou, Mahmoud Mudalal, Yao Wang, Jia Wang, Ming Gong, and Yanmin Zhou.
• Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun.
• Medicine (Baltimore). 2020 Oct 2; 99 (40): e22507.

RationaleIn this report, a combination of platelet-rich fibrin (PRF) membrane and semi-open flap technique was used to improve soft tissue regeneration in immediate implant placement in the molar region. PRF, an autologous fibrin matrix, has been widely used for soft tissue wound healing and regeneration. Semi-open flap technique is beneficial to eliminating exudates and relieving the swelling after surgery.Patient ConcernsCase 1 was a 45-year-old female with a residual crown in the posterior maxillary region that desired a dental implant operation. Case 2 was a 24-year-old male with retained deciduous tooth that requested a restoration of his congenital absent tooth.DiagnosesIn case 1, the tooth 16 was diagnosed with a residual crown, while in case 2, a deciduous tooth 75 was a retained deciduous tooth and 35 was congenital absent.InterventionsIn both cases, immediate implant placement was installed and PRF membranes were made to improve soft tissue augmentation with semi-open flap technique. In case 1, the mixture of an organic bovine bone and blood was filled in the gap between the implant and the socket wall. Subsequently, 2 PRF membranes covered the open wound with semi-open flap. Similarly, in case 2, another 2 PRF membranes were used to improve the soft tissue regeneration, with the same semi-open flap technique as mentioned above.OutcomesIn both cases, successfully soft tissue regeneration was obviously observed without postoperative infection.LessonsUtilizing the PRF membrane combined with semi-open flap technique can achieve excellent soft tissue augmentation around immediate implant placement in the molar regions.

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