• Jason Ju In Chan, Cheng Teng Yeam, Hwei Min Kee, Chin Wen Tan, Rehena Sultana, SiaAlex Tiong HengATHDepartment of Women's Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road Singapore, Singapore City, 229899, Singapore.Duke-NUS Medical School, 8 College Road Singapore, Singapore City, 169857, Singapore., and Ban Leong Sng.
• Department of Women's Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road Singapore, Singapore City, 229899, Singapore.
• BMC Anesthesiol. 2020 Oct 9; 20 (1): 261.

BackgroundPre-operative anxiety is common and is associated with negative surgical outcomes. Virtual reality (VR) is a promising new technology that offers opportunities to modulate patient experience and cognition and has been shown to be associated with lower levels of anxiety. In this study, we investigated changes in pre-operative anxiety levels before and after using VR in patients undergoing minor gynecological surgery.MethodsPatients who underwent elective minor gynecological surgeries in KK Women's and Children's hospital, Singapore were recruited. The VR intervention consisted of 10-min exposure via a headset loaded with sceneries, background meditation music and breathing exercises. For the primary outcome of pre-operative anxiety, patients were assessed at pre- and post-intervention using the Hospital Anxiety and Depression Scale (HADS). Secondary outcomes of self-reported satisfaction scores and EuroQol 5-dimension 3-level (EQ-5D-3L) were also collected.ResultsData analysis from 108 patients revealed that HADS anxiety scores were significantly reduced from 7.2 ± 3.3 pre-intervention to 4.6 ± 3.0 post-intervention (p < 0.0001). Furthermore, HADS depression scores were significantly reduced from 4.7 ± 3.3 pre-intervention to 2.9 ± 2.5 post-intervention (p < 0.0001). Eighty-two percent of the patients self-reported VR intervention as 'Good' or 'Excellent'. EQ-5D-3L showed significant changes in dimensions of 'usual activities' (p = 0.025), 'pain/discomfort' (p = 0.008) and 'anxiety/ depression' (p < 0.0001).ConclusionsFor patients undergoing minor gynecological procedures, the VR intervention brought about a significant reduction in pre-operative anxiety. This finding may be clinically important to benefit patients with high pre-operative anxiety without the use of anxiolytics.Trial RegistrationThis study was registered on clinicaltrials.gov registry ( NCT03685422 ) on 26 Sep 2018.

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