• Drugs of today · Mar 2013

    Carfilzomib for the treatment of multiple myeloma.

    • J Lue, S Goel, and A Mazumder.
    • New York University Langone Medical Center, New York, NY, USA.
    • Drugs Today. 2013 Mar 1; 49 (3): 171-9.

    AbstractCarfilzomib is a second-generation selective proteasome inhibitor that has been recently approved in the use for refractory multiple myeloma. It has been shown to be beneficial in both bortezomib-resistant and bortezomib-naive patients, with a tolerable side effect profile. Peripheral neuropathy is less common in patients receiving carfilzomib compared to bortezomib. Recent and ongoing clinical trials are establishing the role of carfilzomib in the treatment of refractory multiple myeloma.Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

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