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Diabetes Res. Clin. Pract. · Dec 2015
Meta AnalysisIncretin-based therapies are associated with acute pancreatitis: Meta-analysis of large randomized controlled trials.
- Pavel S Roshanov and Brittany B Dennis.
- Schulich School of Medicine and Dentistry, Western University, 1465 Richmond St, London, ON N6G 2M1, Canada. Electronic address: proshano@uwo.ca.
- Diabetes Res. Clin. Pract. 2015 Dec 1; 110 (3): e13-7.
AbstractPrevious studies have offered weak and conflicting evidence regarding the impact of incretin-based oral antihyperglycemic agents on risk of acute pancreatitis. This meta-analysis of three recent mega-trials found an 82% increase in the odds of acute pancreatitis with the use of these agents compared to usual care (95% CI, 1.17-2.82).Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
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