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Journal of neurovirology · Jun 2017
ReviewMolecular and cellular insights into Zika virus-related neuropathies.
- Kai Zhou, Long Wang, Di Yu, Hesuyuan Huang, Hong Ji, and Xuming Mo.
- Department of Cardiothoracic Surgery, Children's Hospital of Nanjing Medical University, Nanjing, 21008, China.
- J. Neurovirol. 2017 Jun 1; 23 (3): 341-346.
AbstractZika virus (ZIKV), a relatively elusive Aedes mosquito-transmitted flavivirus, had been brought into spotlight until recent widespread outbreaks accompanied by unexpectedly severe clinical neuropathies, including fetal microcephaly and Guillain-Barré syndrome (GBS) in the adult. In this review, we focus on the underlying cellular and molecular mechanisms by which vertically transmitted microorganisms reach the fetus and trigger neuropathies.
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