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Case Reports
Drug-induced liver injury in a COVID-19 patient: potential interaction of remdesivir with P-glycoprotein inhibitors.
- Emiel Leegwater, Anne Strik, Erik B Wilms, Liesbeth B E Bosma, David M Burger, Thomas H Ottens, and Cees van Nieuwkoop.
- Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, The Netherlands.
- Clin. Infect. Dis. 2021 Apr 8; 72 (7): 1256-1258.
AbstractWe report a case of a man with COVID-19 who developed acute hepatotoxicity related to remdesivir with probable interaction of P-glycoprotein (P-gp) inhibitors. Until further details on this interaction become available, we recommend physicians to be cautious with the prescription of P-gp inhibitors in patients receiving remdesivir therapy.© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
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