• Emerg. Med. Clin. North Am. · Feb 2021

    Review

    Approach to Acute Weakness.

    • Deena Khamees and William Meurer.
    • Emergency Medicine, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5303, USA.
    • Emerg. Med. Clin. North Am. 2021 Feb 1; 39 (1): 173-180.

    AbstractWeakness has a broad differential diagnosis. A paradigm for organizing possibilities is to consider what part of the nervous system is involved, ranging from brain, spinal cord, nerve roots, and peripheral nerves to the neuromuscular junction. The clinician can consider internal versus external causes. Some neurologic conditions have subtle presentations yet carry a risk of short-term decompensation if not recognized. It is helpful to consider whether an emergency department presentation of weakness is a new disease process or represents an exacerbation of an established condition. Emergency presentations of weakness are challenging, and one must carefully consider potential serious causes.Copyright © 2020 Elsevier Inc. All rights reserved.

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