• Indian J Anaesth · May 2013

    Kounis syndrome resulting from anaphylaxis to diclofenac.

    • Akhilesh Kumar Tiwari, Gaurav Singh Tomar, Col S Ganguly, and Mukul Chandra Kapoor.
    • Department of Anaesthesia, Sushruta Trauma Centre, Civil Lines, New Delhi, India.
    • Indian J Anaesth. 2013 May 1; 57 (3): 282-4.

    Abstract"Kounis syndrome" refers to acute coronary syndromes of varying degree (myocardial ischaemia to infarction) induced by mast cell activation as a result of allergic and anaphylactic reactions. ST-segment elevated myocardial infarction is a rare complication that can occur even in patients with normal coronary arteries due to anaphylactic reactions. We present a case that developed acute myocardial infarction following a diclofenac sodium-induced anaphylaxis. The patient did not have any previous coronary artery disease, but there was a temporal relationship with development of the anaphylactic reaction due to diclofenac sodium and the cardiac event. The patient was managed conservatively and the recovery was uneventful.

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