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Multicenter Study Comparative Study
Outcome of community- versus hospital-acquired intra-abdominal infections in intensive care unit: a retrospective study.
- Timothée Abaziou, Fanny Vardon-Bounes, Jean-Marie Conil, Antoine Rouget, Stéphanie Ruiz, Marion Grare, Olivier Fourcade, Bertrand Suc, Marc Leone, Vincent Minville, and Bernard Georges.
- Département D'Anesthésie-Réanimation (Department of Anesthesia and ICU), CHU Rangueil (University Hospital Centre of Rangeuil), 1 Avenue du Professeur Jean Poulhes TSA 50032, 31059, Toulouse, France. TAbaziou@chu-grenoble.fr.
- BMC Anesthesiol. 2020 Dec 1; 20 (1): 295.
BackgroundTo compare patients hospitalised in the intensive care unit (ICU) after surgery for community-acquired intra-abdominal infection (CA-IAI) and hospital-acquired intra-abdominal infection (HA-IAI) in terms of mortality, severity and complications.MethodsRetrospective study including all patients admitted to 2 ICUs within 48 h of undergoing surgery for peritonitis.ResultsTwo hundred twenty-six patients were enrolled during the study period. Patients with CA-IAI had an increased 28-day mortality rate compared to those with HA-IAI (30% vs 15%, respectively (p = 0.009)). At 90 days, the mortality rates were 36.7 and 37.5% in the CA-IAI group and HA-IAI group, respectively, with a similar APACHE II score on admission (median: 21 [15-25] vs. 21 [15-24] respectively, p = 0.63). The patients with HA-IAI had prolonged ICU and hospital stays (median: 17 [7-36] vs. 6[3-12] days, p < 0.001 and 41 [24-66] vs. 17 [7-32] days, p = 0.001), and experienced more complications (reoperation and reintubation) than those with CA-IAI.ConclusionCA-IAI group had higher 28-day mortality rate than HA-IAI group. Mortality was similar at 90 days but those with HA-IAI had a prolonged ICU and hospital stay. In addition, they developed more complications.
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