• Yasumasa Kawano, Atsushi Togawa, Yoshihiko Nakamura, Mariko Mizunuma, Reiko Yamasaki, Kota Hoshino, Takeshi Nishida, and Hiroyasu Ishikura.
• Department of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, Japan.
• Singap Med J. 2017 Apr 1; 58 (4): 196-200.

IntroductionCandidaemia, recognised as a fairly common disease among intensive care unit (ICU) patients, carries a poor prognosis. However, as studies on the prognostic factors associated with candidaemia in ICU patients are limited, this study aimed to establish the best prognostic factor for ICU patients with candidaemia in a tertiary care hospital in Japan.MethodsWe conducted a retrospective cohort study of patients with candidaemia in the emergency ICU at Fukuoka University Hospital, Fukuoka, Japan, from April 2010 to March 2015. Demographic and clinical data was collected from the patients' medical records and laboratory databases.ResultsA total of 25 patients were included in the study. However, 18 patients died during hospitalisation, resulting in an in-hospital mortality rate of 72.0%. The variables of Sequential Organ Failure Assessment (SOFA) score and cumulative number of risk factors for invasive candidiasis showed significant differences between patients in the survivor and non-survivor groups (p < 0.05). The areas under the receiver operating characteristic curves for the SOFA score and cumulative number of risk factors for invasive candidiasis were 0.873 (95% confidence interval [CI] 0.72-1.00) and 0.937 (95% CI 0.84-1.00), respectively.ConclusionOur results suggest that the cumulative number of risk factors for invasive candidiasis was the most useful prognostic indicator for candidaemia in ICU patients.Copyright: © Singapore Medical Association

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