• Presse Med · Jan 2016

    [Asbestos and respiratory diseases].

    • Arnaud Scherpereel.
    • CHU de Lille, institut Pasteur de Lille, université de Lille, pneumologie et oncologie thoracique, CIIL, Inserm U1019, 59000 Lille, France. Electronic address: arnaud.scherpereel@chru-lille.fr.
    • Presse Med. 2016 Jan 1; 45 (1): 117-32.

    AbstractPrevious occupational asbestos exposure (more rarely environmental or domestic exposure) may induce various pleural and/or pulmonary, benign or malignant diseases, sometimes with a very long latency for malignant mesothelioma (MM). Asbestos has been widely extracted and used in Western countries and in emerging or developing countries, resulting in a peak of MM incidence in France around 2020 and likely in a world pandemic of asbestos-induced diseases. These patients have mostly benign respiratory diseases (pleural plugs) but may also be diagnosed with lung cancer or malignant pleural mesothelioma, and have a global poor outcome. New therapeutic tools (targeted therapies, immunotherapy…) with first promising results are developed. However, it is crucial to obtain a full ban of asbestos use worldwide, and to do a regular follow-up of asbestos-exposed subjects, mostly if they are already diagnosed with benign respiratory diseases. Finally, new cancers (larynx and ovary) were recently added to the list of asbestos-induced tumors.Copyright © 2015 Elsevier Masson SAS. All rights reserved.

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