• Pediatric emergency care · Jan 2021

    Case Reports

    Toddler With Intermittent Abnormal Behavior: Is It Isoniazid-Induced Psychosis?

    • Indar Kumar Sharawat and Lesa Dawman.
    • From the Department of Paediatrics, VMMC & Safdarjung Hospital.
    • Pediatr Emerg Care. 2021 Jan 1; 37 (1): e60e61e60-e61.

    AbstractPsychosis is a state of altered behavior and mentation, and it is rarely reported in preschool children. Isoniazid is a commonly used drug in the treatment and prophylaxis of tuberculosis. It may cause psychosis in overdose but rarely with usual recommended doses. We report a case of drug-induced psychosis secondary to isoniazid intake in a 3-year-old child. She developed intermittent abnormal behavior for 2 weeks after intake of isoniazid. Drug-induced psychosis was a possibility, and the responsible drug was stopped. She improved following the withdrawal of isoniazid.Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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