• Kwang Seog Kim, Dong Gyu Lee, Do Hun Lee, Jae Ha Hwang, and Sam Yong Lee.
• Institution: Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School, Gwangju, Republic of Korea.
• Medicine (Baltimore). 2021 Jan 15; 100 (2): e23611e23611.

RationaleNeurofibromas can develop as part of neurofibromatosis or as a solitary tumor. Although solitary neurofibromas generally grow slowly, they rarely grow for more than 10 years, and such tumors have not been described in the hand.Patient ConcernsA 60-year-old woman presented with a mass on the dorsum of the proximal phalanx of the right thumb that had been enlarging since more than a decade.DiagnosesPreoperative imaging revealed a moderately defined soft tissue mass, which measured 1.5 cm × 1.5 cm × 0.7 cm, with no bone and joint abnormalities on the right thumb. The final diagnosis of the tumor was solitary neurofibroma without evidence of neurofibromatosis.InterventionEn bloc resection of the tumor was performed through a longitudinal skin incision.OutcomesAfter surgery, the patient had no complaints of pain but had a temporary tingling sensation. After 14 months of follow-up, no signs of recurrence of the tumor were observed and she was highly satisfied with the results of the surgery.LessonsSolitary neurofibroma is quite rare, especially one in the hand. However, in dealing with soft tissue tumors of the hand, particularly those with neurologic symptoms, neurofibroma should be included in the differential diagnosis.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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