• Jing Zhang, Yujia Xie, Jia Li, Mingxing Yuan, Zongming Yu, Yue Su, Qianxiang Dai, and Yuan Liu.
• School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
• Medicine (Baltimore). 2021 Jan 15; 100 (2): e24126e24126.

BackgroundSciatica is a syndrome characterized by sciatic nerve path and distribution area pain. Many kinds of literature reported the definite effect of warm needle acupuncture (WNA) on sciatica. However, there is no systematic review or meta-analysis on WNA for sciatica. Therefore, this study will design a protocol to comprehensively and systematically evaluate the effectiveness and safety of WNA on sciatica.MethodsThe two researchers in this study will search the electronic database for randomized controlled trials, (RCTs) of WNA on sciatica, The databases we will search include PubMed, EMBASE, Cochrane Library, Web of Science, Chinese national knowledge infrastructure (CNKI), China Science and Technology Journal Database (VIP), Wanfang Database, and Chinese biomedical literature database (CBM). Review Manager 5.4 software and Cochrane risk bias tool will be us used for data analysis and to evaluate research quality. The main clinical indicators will include visual analogue scale (VAS) and Oswestry Disability Index (ODI).ResultsThis study will evaluate the efficacy and safety of WNA for sciatica.ConclusionThis study will provide a reliable scheme for objectively and comprehensively evaluating the efficacy and safety of WNA on sciatica.Trial Registration NumberINPLASY2020110074.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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