• Ya Jin, Lin Li, and Fan Yang.
• Department of Ultrasound.
• Medicine (Baltimore). 2021 Jan 15; 100 (2): e24242e24242.

RationaleThe drastic differences in treatment and prognosis of infantile hepatic hemangioma (IHH) and hepatoblastoma (HBL) make accurate prenatal diagnosis imperative. The retrospective comparisons of ultrasonic features between fetal IHH and HBL have been reported before, but clinically, the differential diagnosis in utero is very difficult and can lead to prenatal misdiagnosis.Patient ConcernsA 27-year-old woman at 30 gestational weeks underwent the routine prenatal examination. A heterogeneous solid mass of the fetus, with close relationship to the liver, was recognized by ultrasound.DiagnosisA diagnosis of HBL was highly considered.InterventionsThe fetus was aborted and the autopsy was performed.OutcomesThe histological outcome was IHH.LessonsThe prognosis of fetal IHH and HBL is very different, so an accurate diagnosis prenatally is crucial and indispensable. The radiologist and clinician should differentiate between IHH and HBL, especially since the fetus can have serious complications.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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