• Maurizio Marra, Rosa Sammarco, Iolanda Cioffi, Delia Morlino, Olivia Di Vincenzo, Enza Speranza, and Fabrizio Pasanisi.
• Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy. Electronic address: marra@unina.it.
• Nutrition. 2021 Apr 1; 84: 111105.

ObjectiveThe aim of this study was to develop and validate new predictive equations for estimating resting energy expenditure (REE) in subjects with normal weight and overweight, considering anthropometric parameters as well as raw variables from bioimpedance analysis (BIA).MethodsAdult participants with normal weight and overweight were recruited and randomly split into calibration and validation groups. Indirect calorimetry (IC) and BIA were performed in all subjects. New predictive equations were developed using the following models: model 1 with age, weight, stature, and body mass index (BMI) as predictors; and model 2: model 1 + raw BIA variables (bioimpedance index and phase angle). The accuracy of the new equations at both the group (bias) and individual (within ±10%) levels was tested in the validation group. Three published predictive equations were also compared, with the REE values measured by IC.ResultsA total of 2483 adults were included for developing and validating the new equations. All selected formulas, including the new ones, showed a bias of <5% in estimating REE at the group level. Accuracy at the individual level was slightly higher for the new equations, especially for the equation based on raw BIA variables (men = 70.3%; women = 72.3%).ConclusionsCompared to the equations in the literature, the new equations showed good accuracy at both the group and individual levels, with a slight improvement in individual accuracy for the formula including raw BIA variables. However, future research is required to verify the role of the raw BIA variables in predicting REE in subjects with normal weight and overweight.Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.

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