• Medicine · Jan 2021

    Meta Analysis

    Efficacy and safety of Chinese medicine for obstructive sleep apnea: A protocol for systematic review and meta-analysis.

    • Jun-Li Bao, Xinyuan-GaoHeilongjiang University of Chinese Medicine, No.24, Xiangfang District., Yu-Bo Han, Ke Zhang, and Li Liu.
    • Heilongjiang University of Chinese Medicine, No.24, Xiangfang District.
    • Medicine (Baltimore). 2021 Jan 22; 100 (3): e23903e23903.

    BackgroundObstructive sleep apnea (OSA) is significant public concern. Clinical practice indicates that Chinese medicine has certain therapeutic advantages, while there is a lack of evidence-based medicine support. The aim of this study is to synthesize related data to explore efficacy and safety of Chinese medicine for OSA.MethodsData in PubMed, Embase, Web of Science, CNKI, WanFang, VIP databases were comprehensively searched. All the randomized controlled trials (RCTs) in OSA children were identified, in which the effects of Chinese medicine on a range of outcomes were compared. The search had a deadline of January 1, 2020. Two investigators independently conducted data extraction and assessed the literature quality of the included studies. The Revman5.3 software was used for meta-analysis of the included literature.ResultsThe efficacy and safety of Chinese medicine for OSA were evaluated in terms of apnea hypopnea index (AHI, the average and lowest blood oxygen, the Epworth Sleep Scale [ESS], and adverse effects).ConclusionsThis study provides reliable evidence-based support for the clinical application of Chinese medicine for OSA.Prospero Registration NumberCRD42020154864.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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