• Medicine · Jan 2021

    Impact of regulatory T cells on the prognosis of hepatocellular carcinoma: A protocol for systematic review and meta analysis.

    • Xinhui Shi, Qisong Li, and Yungang Wang.
    • Department of Medical Laboratory, Yancheng No.1 People's Hospital & Yancheng First Hospital Affiliated Hospital of Nanjing University Medical School.
    • Medicine (Baltimore). 2021 Jan 22; 100 (3): e23957.

    BackgroundThis meta-analysis aimed to systematically review current available literature to assess the impact of regulatory T cells (Tregs) on the prognosis of hepatocellular carcinoma (HCC).MethodsWe will browse the online databases of PubMed and Cochrane Library. The summary hazard ratio (HR) and their 95% confidence intervals (CIs) will be combined to present the value reported in the study.ConclusionOur meta-analysis will provide useful guidance in treatment of HCC based on the reported evidences regarding the impact of Tregs on the prognosis of HCC.Osf Registration Number10.17605/OSF.IO/3Q8PW.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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