• Sung Hoon Cho, Young Seok Han, Ja Ryung Han, Hyung Jun Kwon, Seock Hwan Choi, Hyun Tae Kim, Man-Hoon Han, and Jae Min Chun.
• Department of Surgery.
• Medicine (Baltimore). 2021 Jan 22; 100 (3): e24037.

RationaleGallbladder polyps are common in the general population, but gallbladder metastasis of renal cell carcinoma (RCC) is very rare. In a patient with RCC diagnosed with a small gallbladder polyp that does not meet the traditional size criteria, the surgeon faces a dilemma of whether cholecystectomy should be performed given the possibility of metastasis.Patient ConcernsA 55-year-old man who had received a left nephrectomy for RCC presented with a gallbladder polyp that was noted at the time of the nephrectomy. Imaging showed the maximum diameter of the polyp had increased from 5 mm to 24 mm in the 40 months after the initial diagnosis.DiagnosisPathological and immunohistology findings confirmed the gallbladder polyp as a metastasis of clear-cell RCC.Interventions: We performed a laparoscopic cholecystectomy.OutcomesEven though the synchronous solitary gallbladder metastasis was left untreated and a cholecystectomy was not performed over the 40 months, no metastasis occurred in other sites. The patient is free from disease 10 months after the cholecystectomy.LessonsSolitary gallbladder metastasis of RCC may have more favorable outcomes than typical metastases. Although gallbladder metastasis of RCC occur rarely, it can occur, and any changes in gallbladder polyps in RCC patients should be managed under a strong suspicion of metastasis.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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