• Medicine · Jan 2021

    Comparative Study

    Medium and long-term complications difference between laparoscopic transcystic common bile duct exploration versus endoscopic sphincterotomy against choledocholithiasis: A protocol for systematic review and meta-analysis.

    • Quanxin Liu, Tao Li, Zhangdong Feng, and Wei Han.
    • Beijing Luhe Hospital, Capital Medical University, Tongzhou, Beijing.
    • Medicine (Baltimore). 2021 Jan 22; 100 (3): e24104.

    BackgroundCommon bile duct stone (CBDS) is typically manifested with abdominal pain, chills, fever, and jaundice. Laparoscopic transcystic common bile duct exploration (LTCBDE) and endoscopic sphincterotomy (EST) are currently the main minimally invasive methods for the treatment of CBDS. However, there are few studies about the differences of medium and long-term complication after EST or LTCBDE. Therefore, we will conduct a meta-analysis and systematic review to systematically evaluate the difference of medium and long-term complications between EST and LTCBDE against CBDS.MethodsRandomized controlled trials of EST or LTCBDE against CBDS will be searched in several English and Chinese databases with the following vocabularies: "laparoscopic transcystic common bile duct exploration," "endoscopic sphincterotomy," "choledocholithiasis," "common bile duct stone" until December, 2020. Two reviewers will independently conduct the literature extraction, risk of bias assessment, and statistical analysis.Results And ConclusionsThe study will help to systematically evaluate the difference of medium and long-term complication between EST and LTCBDE against CBDS.Osf Registration NumberDOI 10.17605/OSF.IO/5U7SA.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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