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The Journal of infection · Jan 1990
Case ReportsEarly-onset neonatal pneumococcal sepsis in siblings.
- E D Wright, J E Lortan, and R M Perinpanayagam.
- Department of Microbiology, Queen Mary's University Hospital, Roehampton, London, U.K.
- J. Infect. 1990 Jan 1; 20 (1): 59-63.
AbstractThe case of a woman who in two successive pregnancies produced premature infants affected by early-onset Streptococcus pneumoniae type 8 sepsis is described. Low maternal levels of pneumococcal IgG antibodies were demonstrated after the second delivery, and vaccination with 'Pneumovax' produced a rise in antibody levels. Attention is drawn to the similarity between early-onset pneumococcal neonatal sepsis and group B streptococcal sepsis. Mothers of infants affected by early-onset pneumococcal sepsis who have low pneumococcal antibody levels run the risk of subsequent babies being similarly affected and vaccination should be considered to prevent recurrence.
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