• Medicina · Jan 2020

    Case Reports

    [Malignant syphilis in a patient with HIV infection].

    • María Cecilia Garbarino, Carla Trila, Leandro Heffner, María Eugenia Cantón, Florencia Quadrana, and Marcelo Zylberman.
    • División Clínica Médica, Hospital General de Agudos Dr. Cosme Argerich, Buenos Aires, Argentina. E-mail: garbarinomc@gmail.com.
    • Medicina (B Aires). 2020 Jan 1; 80 (6): 714-717.

    AbstractMalignant syphilis occurs frequently in patients infected with human immunodeficiency virus (HIV) and presents with cutaneous nodular lesions that tend to ulcerate. Non caseating granulomas are among the most conspicuous histopathological findings and require differential diagnosis with other infectious and non-infectious granulomatous conditions. The evolution of the disease is usually favourable with penicillin treatment. We present the case of an HIV-positive patient who meets diagnostic criteria for malignant syphilis and alert on this infrequent granulomatous entity.

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