Liver and Kidney Transplantation: A Half-Century Historical

Med. Clin. North Am. · May 2016

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Liver and Kidney Transplantation: A Half-Century Historical Perspective.

This article describes the evolution of solid organ kidney and liver transplantation and expounds on the challenges and successes that the early transplant researchers and clinicians encountered. The article highlights the surgical pioneers, delves into the milestones of enhanced immunosuppression protocols, discusses key federal legislative and policy changes, and expounds on the ongoing disparities of organ supply and demand and the need for extended criteria and live donor organs to combat these shortages. Finally, recent changes in organ allocation and distribution policies are discussed. The authors also spotlight novel interventions that will further revolutionize abdominal transplantation in the next 50 years.

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- David A Sass and Alden M Doyle.
- Liver Transplantation, Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospitals, Sidney Kimmel Medical College at Thomas Jefferson University, 132 South 10th Street, Suite 480, Main Building, Philadelphia, PA 19107, USA. Electronic address: David.Sass@jefferson.edu.
- Med. Clin. North Am. 2016 May 1; 100 (3): 435-48.
AbstractThis article describes the evolution of solid organ kidney and liver transplantation and expounds on the challenges and successes that the early transplant researchers and clinicians encountered. The article highlights the surgical pioneers, delves into the milestones of enhanced immunosuppression protocols, discusses key federal legislative and policy changes, and expounds on the ongoing disparities of organ supply and demand and the need for extended criteria and live donor organs to combat these shortages. Finally, recent changes in organ allocation and distribution policies are discussed. The authors also spotlight novel interventions that will further revolutionize abdominal transplantation in the next 50 years.Copyright © 2016 Elsevier Inc. All rights reserved.

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Liver and Kidney Transplantation: A Half-Century Historical Perspective.

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