• Presse Med · Jan 2018

    Review

    [Focus on Achalasia].

    • Marie-Anne Guillaumot, Maximilien Barret, Sarah Leblanc, Mahaut Leconte, Bertrand Dousset, Ammar Oudjit, Frédéric Prat, and Stanislas Chaussade.
    • Hôpital Cochin, service de gastroentérologie, 75014 Paris, France; Faculté Paris Descartes, 75014 Paris, France.
    • Presse Med. 2018 Jan 1; 47 (1): 11-18.

    AbstractThe pathophysiology of achalasia is largely unknown, and involves the destruction of ganglion cell in the esophageal myenteric plexus. High-resolution esophageal manometry is the key investigation. Endoscopic pneumodilatation and laparoscopic Heller myotomy have comparable short-term success rates, around 90%. The main complication after pneumodilatation is esophageal perforation, occurring in about 1% of cases. Peroral endoscopic myotomy is a promising treatment modality, however with frequent post-procedural gastroesophageal reflux.Copyright © 2017 Elsevier Masson SAS. All rights reserved.

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