• Medicine · Mar 2021

    Review Case Reports

    Reversible leukoencephalopathy caused by 2 rodenticides bromadiolone and fluoroacetate: A case report and literature review.

    • Aili Lu, Fang Yuan, Yufei Yao, Wanxin Wen, Hongji Lu, Shibiao Wu, and Lixin Wang.
    • The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
    • Medicine (Baltimore). 2021 Mar 5; 100 (9): e25053e25053.

    RationaleWith the easy access, rodenticide poisoning has been a public health problem in many countries. Characteristics of central nervous system (CNS) lesions induced by rodenticides are scarcely reported.Patient ConcernsWe presented a case of a 40-year-old man with seizure and consciousness disorder, coagulation dysfunction, and symmetric lesions in white matter and corpus callosum.DiagnosisHe was diagnosed with rodenticide poisoning due to bromadiolone and fluoroacetamide.InterventionsHe was treated with vitamin K, hemoperfusion, acetamide, and calcium gluconate.OutcomesHis leukoencephalopathy was reversed rapidly with the improvement of clinical symptoms.LessonsThis report presented the impact of rodenticide poisoning on CNS and the dynamic changes of brain lesions, and highlighted the importance of timely targeted treatments.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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