• V Karande, S Levrant, R Hoxsey, J Rinehart, and N Gleicher.
• Division of GynecoRadiology, Center for Human Reproduction, Illinois, Chicago 60610, USA.
• Fertil. Steril. 1997 Oct 1; 68 (4): 658-62.

ObjectiveTo present further experience with in-office lysis of intrauterine adhesions under fluoroscopic control using a specially designed catheter.DesignProspective study.SettingMedical school-affiliated infertility center.Patient(S)Seventeen infertile patients undergoing routine gynecoradiologic investigation as part of an initial infertility workup.Intervention(S)The initial hysterosalpinography was performed with a commercially available uterine catheter that seals off the uterine cavity before injection of contrast. If intrauterine adhesions were diagnosed, an immediate attempt at lysis was made using the catheter's balloon tip or hysteroscopic scissors, which were inserted through the main port of the catheter. The procedures were carried out using a paracervical block or IV analgesia.Main Outcome Measure(S)Normal uterine cavity after lysis of intrauterine adhesions.Result(S)Seventeen patients underwent lysis of intrauterine adhesions. In 13 patients (9 mild, 3 moderate, and 1 severe), the adhesions were lysed successfully (81.2%). Among those, nine procedures were performed with the balloon and four with scissors. In 4 cases (2 moderate and 2 severe), lysis of adhesions was only partially successful. These procedures had to be abandoned prematurely because of patient discomfort before attempting the use of scissors (n = 1), extravasation of dye into the myometrium making visualization difficult (n = 1), and thick, fibrotic adhesions that were resistant to scissors (n = 2).Conclusion(S)In-office lysis of intrauterine adhesions under gynecoradiologic control can be carried out safely in the majority of patients, using minimally invasive techniques. The potential cost savings in comparison with endoscopic procedures, which require utilization of expensive operating room time, are especially relevant in today's cost-conscious managed care environment. Only failures of in-office procedures would reach the operating room under the algorithm proposed here.

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