• Tong Yu, Jiu-Ping Wu, Jun Zhang, Hai-Chi Yu, Tian-Yang Yuan, De-Rui Xu, Zhi-He Yun, Tao He, Rui Liu, and Qin-Yi Liu.
• Department of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
• Medicine (Baltimore). 2021 Mar 19; 100 (11): e24220e24220.

IntroductionTraditional open discectomy and intervertebral fusion surgery is the common strategy for lumbar disc herniation (LDH). However, it has the disadvantages of long recovery time and severe paravertebral soft tissue injury. Zina percutaneous screw fixation combined with endoscopic lumbar intervertebral fusion (ZELIF), as a novel minimally invasive surgical technique for LDH, has the advantages in quicker recovery, less soft tissue destruction, shorter hospital stays and less pain. We report a novel technique of ZELIF under intraoperative neuromonitoring (INM) for the treatment of LDH.Patient ConcernsA 51-year-old male presented to our hospital with left lower extremity pain and numbness for 1 year.DiagnosisLumbar disc herniation (LDH).InterventionsThis patient was treated with Zina percutaneous screw fixation combined with endoscopic neural decompression, endplate preparation, and intervertebral fusion through Kambin's triangle. Each step of the operation was performed under INM.OutcomesThe follow-up period lasted 12 months; the hospitalization lasted 4 nights; the blood loss volume was 65 ml, and the time of operation was 266 min. INM showed no neurological damage during the surgery. No surgical complications, including neurological deterioration, cage migration, non-union, instrumentation failure or revision operation, were observed during the follow-up period. Visual Analogue Scale (VAS) score reduced from 7 to 1; the Oswestry Disability Index (ODI) decreased from 43 to 14; the EQ-5D score was 10 preoperatively and 15 at the final follow-up visit; the Physical Component Summary of the 36-Item Short Form Health Survey (SF-36) was 48 preoperatively and 49 at the last follow up visit; the SF-36 Mental Component Summary was 47 before surgery and decreased to 41 postoperatively.ConclusionZELIF under INM may represent a feasible, safe and effective alternative to endoscopic intervertebral fusion and percutaneous screw fixation, for decompressing the lumbar's exiting nerve root directly with minimal invasion in selected patients.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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