• Rev. Soc. Bras. Med. Trop. · Jan 2020

    Case Reports

    Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management.

    • Monique Freire Santana, Guilherme Pivoto, Márcia A Araujo Alexandre, Djane Clarys Baía-da-Silva, Mayla Gabriela da Silva Borba, Fernando Almeida Val, Jose Diego Brito-Sousa, Gisely Cardoso Melo, Wuelton Marcelo Monteiro, João Vicente Braga Souza, Silviane Bezerra Pinheiro, Luiz Carlos Lima Ferreira, Felipe Gomes Naveca, Valdinete Alves Nascimento, André Lima Guerra Corado, Ludhmila Abrahão Hajjar, João Ricardo Silva Neto, George Alan Villarouco Siva, Alessandro C Pasqualotto, and Marcus Vinícius Guimarães Lacerda.
    • Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
    • Rev. Soc. Bras. Med. Trop. 2020 Jan 1; 53: e20200401.

    AbstractWe present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.

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