• Li Fang, Jiaoru Pei, Song Mao, Liangxia Wu, and Siqiong Jiang.
• Department of Pediatrics, Shanghai Sixth People's Hospital, Shanghai, China.
• Medicine (Baltimore). 2021 Apr 23; 100 (16): e25506e25506.

BackgroundIn recent years, more and more reports are focused on the application of traditional Chinese medicine injection (TCMJ) for the treatment of viral pneumonia. There are about 200 million cases of viral pneumonia worldwide every year, half of which are children. At present, many kinds of TCMJ are created for the treatment of viral pneumonia in children, with good therapeutic effects. However, there are many kinds of TCMJ, and the treatment advantages are different, thus bringing difficulties to the selection of clinical drugs. In order to provide evidence-based evidence support for the clinical selection of TCMJ for the treatment of viral pneumonia in children, this study selected the commonly used TCMJ for clinical treatment of viral pneumonia for meta-analysis to evaluate its efficacy.MethodsThe Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang Data, Viper information databases, Cochran library Web of Science, PubMed, MEDLINE and EMBASE will be searched. The literature will be searched, with language restriction in English and Chinese. The related reference will be retrieved as well. Two reviewers will independently extract data and perform quality assessment of included studies. Review Manager 5.3 will be applied to conduct this meta-analysis.ResultsThe results of this systematic review and meta-analysis will be published in a peer-reviewed journal once we finish this study.ConclusionsThis study provides reliable evidence-based evidence for the efficacy of TCMJ in the treatment of viral pneumonia in children.Ethics And DisseminationWe will not be allowed to publish private information from individuals. This kind of systematic review should not harm the rights of participants. No ethical approval was required. The results can be published in peer-reviewed journals or at relevant conferences.Osf Registration NumberDOI 10.17605/OSF.IO/795MB.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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