• J Clin Monit Comput · Aug 2021

    Comment Letter

    Analgesia Nociception Index (ANI) and ephedrine: a dangerous liasion.

    • Rita Graça and Francisco A Lobo.
    • Department of Anesthesiology, Centro Hospitalar de Trás-os-Montes e Alto Douro (CHTMAD), Vila Real, Portugal.
    • J Clin Monit Comput. 2021 Aug 1; 35 (4): 953-954.

    AbstractThe Analgesia Nociception Index is a dimensionless scale derived from the heart rate variability; by analyzing the heart rate variability oscillations, it reflects the activity of the sympathetic and parasympathetic nervous systems and ultimately helps to evaluate the Nociception-Antinociception balance during anesthesia and surgery. Drugs like ephedrine affect the heart rate variability inducing artifacts in the ANI readings which should be taken into account in the clinical practice and in clinical research.© 2021. The Author(s), under exclusive licence to Springer Nature B.V.

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