• J A Bermúdez de la Vega, A Gómez Calzado, M Sobrino Toro, A Alejo Garcia-Mauricio, J Romero Cachaza, and J González Hachero.
• Cátedra de Pediatría y Puericultura de la Facultad de Medicina, Hospital Universitario Virgen Macarena, Sevilla.
• An. Esp. Pediatr. 1993 Sep 1; 39 (3): 214-8.

AbstractWe have studied 50 children affected with acute meningococcal disease (AMD). The ages of the children varied between 4 months and 12.58 years, with a mean age of 4.58 years. By using the shock state and DIC syndrome, both of which are indications of the severity of the illness, an evaluation of the discriminatory capacity was done with regard to significantly associate variables and 3 scores, Bjorvatn, Leclerc and PRISM, throughout 8 intervals within the first 48 hours of hospital treatment. We observed a very high survival rate (98%) associated with the early treatment for shock. Leukopenia and disseminated purpura were the best variables in order to discriminate shock and DIC, respectively. The greatest capacity for the diagnosis of the shock state and DIC syndrome were registered during the 0-6 hour period and the 0-12 hour period, respectively. The prognosis improved if the child remained alive 12 hours after the treatment had begun.

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