• Pediatr. Clin. North Am. · Apr 2014

    Review

    Diagnosis and management of morphea and lichen sclerosus and atrophicus in children.

    • Elena Pope and Ronald M Laxer.
    • Section of Dermatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada. Electronic address: elena.pope@sickkids.ca.
    • Pediatr. Clin. North Am. 2014 Apr 1; 61 (2): 309-19.

    AbstractMorphea (localized scleroderma) is a rare fibrosing disorder of the skin and underlying tissues characterized by skin thickening and hardening due to increased collagen deposition. The significance of the disease depends on the extent of the lesions, potential for functional disability or cosmetic disfigurement, and presence or absence of extracutaneous manifestations. Treatment is tailored; circumscribed forms may require only topical treatment, while forms causing functional impairment or severe cosmetic change may require systemic treatment. Although localized scleroderma has a good prognosis, some clinical subtypes can be deforming and irreversibly disabling, especially when affecting the extremities or the face. Copyright © 2014 Elsevier Inc. All rights reserved.

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