• Mei Long and Xiangchun Zhang.
• Department of Obstetrics and Gynecology, Hubei Huanggang Central Hospital, Hubei Province, China.
• Medicine (Baltimore). 2021 May 7; 100 (18): e25505e25505.

BackgroundThe argument on the efficacy of medical nutritional therapy and comprehensive nutritional care remains to be resolved. Therefore, we conducted this protocol of systematic review and meta-analysis to evaluate the efficacy between medical nutritional therapy and comprehensive nutritional care for patients with gestational diabetes mellitus (GDM).MethodsWe followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols reporting guidelines and the recommendations of the Cochrane Collaboration to conduct this study. Reviewers will search the PubMed, Cochrane Library, Web of Science, and EMBASE online databases using the key phrases "gestational diabetes mellitus," "comprehensive nutrition care," and "medical nutritional therapy" for all cohort studies published up to May 20, 2021. There is no restriction in the dates of publication or language in the search for the current review. The studies on cohort study focusing on comparing medical nutritional therapy and comprehensive nutrition care for GDM patients will be included in our meta-analysis. The outcomes include blood glucose levels, complications, weight change, and incidence of cesarean section. Where disagreement in the collection of data occurrs, this will be resolved through discussion.ResultsWe hypothesized that these 2 methods would provide similar therapeutic benefits.Osf Registration Number10.17605/OSF.IO/SC8HJ.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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