• Medicine · May 2021

    Risk factors of enteral feeding intolerance in severe acute pancreatitis patients: A protocol for systematic review and meta-analysis.

    • Hongyun Fan, Chunchun Yang, Zhiying Duan, Xiaohui Huo, and Yang Yang.
    • The First Hospital of Hebei Medical University, Shijiazhuang.
    • Medicine (Baltimore). 2021 May 7; 100 (18): e25614e25614.

    BackgroundPatients with severe acute pancreatitis (SAP) have gastrointestinal dysfunction, and enteral nutrition intolerance is easy to occur during the implementation of enteral nutrition, which leads to the suspension or termination of enteral nutrition. Enteral nutrition cannot tolerate the influence of many factors. At present, there is a lack of analysis on the influencing factors of enteral nutrition intolerance in patients with SAP. Therefore, this study analyzed the factors of enteral nutrition intolerance in patients with SAP by meta-analysis, to provide a basis for the protection of enteral nutrition in patients with SAP.MethodsDatabases (PubMed, Embase, Cochrane Library, Web of Science, China Biology Medicine Database, China National Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang) were searched using index words to find relevant studies published before March 2021. Meta-analyses of relative risk were performed for the identification of risk factors.ResultsWe will disseminate the findings of this systematic review and meta-analysis via publications in peer-reviewed journals.ConclusionThis study systematically reviewed the existing evidence and determined the incidence and predictors of enteral nutrition intolerance in patients with SAP.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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