• Ida K Fox, Christine B Novak, Emily M Krauss, Gwendolyn M Hoben, Craig M Zaidman, Rimma Ruvinskaya, Neringa Juknis, Anke C Winter, and Susan E Mackinnon.
• Division of Plastic & Reconstructive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Box 8238, St Louis, MO 63110(∗). Electronic address: foxi@wustl.edu.
• PM R. 2018 Nov 1; 10 (11): 1173-1184.e2.

BackgroundNerve transfer surgery to restore upper extremity function in cervical spinal cord injury (SCI) is novel and may transform treatment. Determining candidacy even years post-SCI is ill defined and deserves investigation.ObjectiveTo develop a diagnostic algorithm, focusing on electrodiagnostic (EDX) studies, to determine eligibility for nerve transfer surgery.DesignRetrospective descriptive case series.SettingTertiary university-based institution.PatientsIndividuals with cervical SCI (n = 45).MethodsThe electronic medical records of people referred to the Plastic Surgery Multidisciplinary Upper Extremity Surgery in SCI clinic from 2010-2015 were reviewed. People were considered for nerve transfers to restore elbow extension or finger flexion and/or extension. Data including demographic, clinical evaluation, EDX results, surgery, and outcomes were collected and analyzed.Main Outcome MeasurementsEDX data, including nerve conduction studies and electromyography, for bilateral upper extremities of each patient examined was used to assess for the presence of lower motor neuron injury, which would preclude late nerve transfer.ResultsBased on our criteria and the results of EDX testing, a substantial number of patients presenting even years post-SCI were candidates for nerve transfers. Clinical outcome results are heterogeneous but promising and suggest that further refinement of eligibility, long-term follow-up, and standardized assessment will improve our understanding of the role of nerve transfer surgery to restore function in people with midcervical SCI.ConclusionsMany patients living with SCI are candidates for nerve transfer surgery to restore upper extremity function. Although the ultimate efficacy of these surgeries is not yet determined, this study attempts to report the criteria we are using and may ultimately determine the timing for intervention and which transfers are most useful for this heterogeneous population.Level Of EvidenceIV.Copyright © 2018 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

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